But what’s truly remarkable is that her work represents just one front of a broad revolution in genetics sparked by the technique called CRISPR-Cas9. Just four years old, this discovery is transforming research into how to treat disease, what we eat and how we’ll generate electricity, fuel our cars and even save endangered species. Experts believe that CRISPR can be used to reprogram the cells not just in humans but also in plants, insects–practically any piece of DNA on the planet. On June 2, a scientist at MIT and Harvard’s Broad Institute announced the development of a related CRISPR technique that can edit RNA, which is responsible for regulation and expression of genes. If DNA is the genetic alphabet, RNA spells actual words. In plain terms, that means the already vast possibilities for CRISPR got even bigger.
He’s a regular at Fab Lab Egypt, a home for aspiring developers that’s become an early building block of the country’s tiny but growing tech scene. In the five years since the so-called Twitter revolution drove President Hosni Mubarak from power, startups, incubators, and angel investors have sprung up like shoots of grass after a drought. “The revolution showed me what people can achieve when they work together,” says Hisham Khodeir, a software engineer who helped found Fab Lab in 2012.
This blog was born on March 7, 2005. Facebook had a different name then. The social network had 3 million, mostly casual users. Today it counts over 1.6 billion. No one had heard of the iPhone. The Google Car. Uber. Or Amazon Web Services.
It has been an amazing run over the last 11 years. And innovation keeps accelerating. This is what Florence must have felt like during the European Renaissance.
And the innovation is spreading globally. Search the blog and you find entries on Rwanda, Kazakhstan, Antarctica and plenty more places off the innovation beaten path.
The blog has influenced 4 of my books. It has helped many of my consulting clients as I “raise the bar” for what they can expect from technology
I am grateful to my sponsors for their continued support. I am thankful to many friends who send me story ideas for posts. And especially thankful to readers who have made this blog part of their regular diet.
Peloton is a startup focused delivering virtual spin classes via distributed video and a $1,995 bike that is also an integrated hardware and software system.
The company, which has been opening up showrooms in major cities and shopping outlets, offers unlimited streaming rides live and on-demand as well as an app with content. Peloton's goal is to use gamification to spur competition and engagement among riders.
The company’s lettuce robot — which scans a field using computer vision and douses just the weeds with deadly fertilizer — seems to be gaining traction in the market. Heraud says that 5 percent of the lettuce produced in the U.S. has been grown in California and Arizona using Blue River lettuce robots. “If you’ve eaten lettuce over the last few months, odds are the lettuce has been scanned by the lettucebot,” says Heraud.
The lettuce bot, which is in its fourth generation, can boost the yield of farms by 10% and can reduce operation costs by replacing human labor. Manually spraying and pulling weeds on a lettuce farms is a difficult job.
The air in the cleanroom is the purest you’ve ever breathed. It’s class 10 purity, meaning that for every cubic foot of air there can be no more than 10 particles larger than half a micron, which is about the size of a small bacteria. In an exceptionally clean hospital OR, there can be as many as 10,000 bacteria-size particles without creating any special risk of infection. In the outside world, there are about 3 million.
The cleanroom is nearly silent except for the low hum of the “tools,” as Intel calls them, which look like giant copy machines and cost as much as $50 million each. They sit on steel pedestals that are attached to the building’s frame, so that no vibrations—from other tools, for instance, or from your footfalls—will affect the chips. You step softly even so. Some of these tools are so precise they can be controlled to within half a nanometer, the width of two silicon atoms.
It’s surprisingly dark, too. For decades, Intel’s cleanrooms have been lit like darkrooms, bathed in a deep, low yellow.
Callahan, a celebrity caterer credited by Martha Stewart with inventing the bite-sized slider, bought his first 3-D plastics printer two years ago to wow guests at a holiday party. Today, he has his sights trained on printing the food itself. He imagined drumsticks with edible bones; could they be made of celery? Blue cheese? Hot sauce? Callahan already makes an edible cracker spoon to use with caviar, but he envisions an entire line of cutlery, plates and menus that could be printed and consumed at parties. He sees mini-milk cartons made of chocolate and Asian-style takeout boxes formed from wontons.
This may look like a fun tree house. But look closer and you find all kinds of high-tech security including a biometric fingerprint lock
“Unique to this project was the high site security required by the client. “Someone from the client’s security detail remained with our craftsmen at every moment — even to the toilet or while waiting outside of the door to enter. My staff was required to hand in their passports, mobile phones and cameras to armed security personnel at the main entrance,” says Payne.”
better materials, autonomous navigation systems, and other technical advances have convinced a growing body of smart, wealthy, and apparently serious people that within the next few years we’ll have a self-flying car that takes off and lands vertically—or at least a small, electric, mostly autonomous commuter plane. About a dozen companies around the world, including startups and giant aerospace manufacturers, are working on prototypes. Furthest along, it appears, are the companies Page is quietly funding. “Over the past five years, there have been these tremendous advances in the underlying technology,” says Mark Moore, an aeronautical engineer who’s spent his career designing advanced aircraft at NASA. “What appears in the next 5 to 10 years will be incredible.”
The Spaceship, as many have nicknamed it, is over one mile in circumference—that's wider than the Pentagon. When it’s completed later this year it will house 13,000 employees—including design grandmaster Jony Ive, who helped sculpt the iPhone, and CEO Tim Cook, who helps keep profits in the “billions-with-a-B” territory.
Campus 2 will run entirely on clean energy, powered by renewable sources. But what’s really grabbed our attention are the thousands of panels of curved window panes—the largest pieces of structural glass ever made—that will encase Apple’s mothership. Equally cool are the 60,000 pounds of hollow concrete slabs that allow the building to “breathe,” bolstering its eco-friendly qualities.
A self-driving John Deere tractor rumbles through Ian Pigott’s 2,000-acre farm every week or so to spray fertilizer, guided by satellite imagery and each plot’s harvesting history. The 11-ton behemoth, loaded with so many screens it looks like an airplane cockpit, relays the nutrient information to the farmer’s computer system. With weather forecasts and data on pesticide use, soil readings, and plant tissue tests pulled by various pieces of software, Pigott can keep tabs on the farm down to the square meter in real time without ever leaving his carpeted office.
“This is becoming more standard,” says Pigott, who grows a rotation of wheat, oilseed, oats, and barley on his farm in the rolling Hertfordshire countryside an hour north of London.
(intelligent Voice)’s CEO Nigel Cannings says the breakthrough came when he decided to see what would happen if he pointed a machine-learning system at the waveform of the voice data – its pattern of spikes and troughs – rather than the audio recording directly. It worked brilliantly.
Training his system on this visual representation let him harness powerful existing techniques designed for image classification. “I built this dialect classification system based on pictures of the human voice,” he says.
Crafting gadgets that can handle these usage scenarios is tricky, though, but Lenovo has a sense of humor about it. When bending the Cplus to curve around someone's wrist, the Android phone's tall display "cracks" -- actually just a software trick that distorts the screen. The Folio, on the other hand, was more straight-laced. Folding the tablet in half bends the screen around the outside of the chassis, effectively turning it into a big ol' phone.
Instead of starting the journey at a dealership on a suburban trading estate. the VR test driver can be instantly transported to the Big Sur, Alpine hairpins or their favorite race track.
Last September. a virtual drive featuring former racing driver, Ben Collins, in a BMW 640M went viral thanks to a 360- degree experience created by a partnership with technology company Rewind. Cutting edge technology stitched together footage from a constellation of cameras to provide the immersive experience.
In March, BMW marked its centennial—and a century of technological rivalry with Daimler’s Mercedes-Benz. In newspaper ads, Benz, which can lay claim to having invented the car in 1886, congratu-mocked its Bavarian archenemy: “Thanks for 100 years of competition. The 30 years before that were a little dull.” That’s like M-B doing doughnuts on BMW’s driveway.
Pitsiladis considered these forecasts to be overly conservative. He started his Sub2 Project in late 2014 with i website, fund-raising and the recruitment of scientists. He believed his goal could be achieved by the end of 2019 — years earlier than commonly thought possible
.His consortium of scientists would use the latest knowledge — and develop culling-edge approaches — in nutrition, biomechanics, genetics, running efficiency, training, race strategy and sports medicine to deliver a sub-two-hour marathon. Incremental gains here and there, the scientists believed, could add up to a startling accomplishment. And perhaps new technology and knowledge would emerge for broader benefits, as when man raced toward the moon.
The Sub2 experts would use data to confront habit, tradition, consensus. They would tailor training programs to individuals, employing science to help runners from Ethiopia and Kenya and elsewhere who had had fantastic performances using little science.
Meet nihonium (Nh), moscovium (Mc), tennessine (Ts) and oganesson (Og), the newest elements on the periodic table to receive names. But don't get too attached to the nomenclature for these elements, formerly known by their respective atomic numbers 113, 115, 117 and 118. The names are on a five-month probation before things are made official.
3D Touch - By weaving 3D Touch more deeply into the fabric of iOS 10—and specifically, making it an essential part of its lock screen—Apple finally arms potentially revolutionary feature with true purpose. You may not use 3D Touch much today, but after iOS 10 arrives this fall, you may wonder how you lived without it.
Siri - Not only that, you’ll be able to use Siri on your PC, to make a lot of simple actions easier: adding things to your calendar, doing quick research and calculations, setting reminders, playing music, even searching your computer. Siri can search Finder, finding you files from last week about the offsite and then showing you the ones you tagged as draft. Click on a button and it pins into your notification center, for easy finding later. The voice assistant can do more on the Apple TV as well: Siri has improved topical searches for movies and TV shows (“Horror movies from the ’80s”) and you can now run voice searches for YouTube videos.
“We totally get it, and that’s why today we’re starting the global roll out of Scheduled Rides. With just a few taps on your app, you can schedule your ride 30 minutes to 30 days in advance and have the comfort of knowing your Uber will be there when it’s time to head out.”
The initiative, previously called Project Tango, is Google's ambitious plan to map the indoor world. Google Maps is already wildly popular, with more than 1 billion users. But where Maps is a cartographer's dream on steroids, Tango isn't concerned with streets and rivers and national parks. Tango is for everything underneath rooftops: hallways, offices, ballrooms and -- perhaps more importantly for Google's advertising ambitions -- the stuff inside those rooms, like furniture and products on shelves.
The 18,000 containers aboard a vast new vessel unveiled this month by shipping giant CMA CGM are more than just climate-controlled cargo boxes. Embedded with technology from French IoT startup TRAXENS, each container is a smart connected object, able to share data with other containers, with the crew’s mobile devices, and with company HQ in Marseille. The devices relay the container’s location, temperature, humidity level, vibrations, any impacts or attempted break ins, and customs clearance status. Monitoring all that for every one of the 5 to 6 million containers in transit on the world’s oceans at any given moment would be a data revolution. It will eventually happen.
But other technologies will also soon transform how the world’s 100,000-plus ocean-going merchant ships are managed, operated, and maintained. Consulting and services firm Lloyd’s Register says the carrier of the future will be “smarter, data driven, greener…fully connected wirelessly onboard, and digitally connected through global satellites.”
Such ships might also be unmanned. Lloyd’s predicts tankers and cargo carriers will be guided by sensors, automation, big data, and global networks. Indeed, Rolls-Royce got to work this summer on a $7.5 million research project for the Finnish Funding Agency for Technology and Innovation to produce specs and designs for a fully remote-controlled ship.
It’s hard to believe Vegas can continue to surprise every time you go back.
A driver told me about the planned Resorts World complex which “will feature 3,100 hotel rooms and a casino spreading over 150,000sq.ft. The resort is expected to be completed and launched early in 2019. The choice of a Chinese theme for the project was not an arbitrary one. Resorts World Las Vegas is to be built with the intention of attracting the attention of Chinese players, particularly ones wealthy enough to travel to the US.”
Two drivers gave me all kinds of trivia about The High-Roller, similar to the Eye in London, which is one heck of a way to see the glamorous city, especially at night.
Several bloggers at the Discover event told me about their experience at TopGolf. HP Enterprise arranged an evening for them at the attraction
Delta has been working on something it calls "innovation lines," a slightly modified version of the normal TSA checkpoints that already bog down every airport. After spending over a million dollars in an attempt to fix the system, it seems like they've arrived at a solution. Even if it's not the best possible option, it's got to be better than what we've got.
Delta's innovation lines rely on a couple of tweaks. Instead of having passengers bin-up their stuff one at a time, the innovation lines have five designated stations so that the whole line isn't held up by one person who can't fish their keys out of their pocket. On top of that, the conveyors move automatically, and cleverly route empty bins back to the stations for the next people who are anxious to get going.
Customers can go cardless in two ways: by using the bank’s app on their phone, or through a mobile wallet such as Apple Pay or Android Pay. Using the app, customers request an access code they then enter on the eATM, like a temporary PIN. The mobile wallet option uses near field communication, or NFC, the same technology you may have used or seen used at the grocery store or the mall, where the customer holds a credit card or phone up to a reader, and the two communicate without any contact. A thumbprint verifies the customer’s ID on the mobile device and enables access to the ATM.
2/3 of of my books have sold in print format so this Guardian article did not really surprise me
“Shrewd observers noted the early signs. Kindle sales initially outstripped hardbacks but have slid fast since 2011. Sony killed off its e-readers. Waterstones last year stopped selling Kindles and e-books outside the UK, switched shelf space to books and saw a 5% rise in sales.
Amazon has opened its first bookshop.
Now the official Publishers’ Association confirms the trend. Last year digital content sales fell last year from £563m to £554m. After years on a plateau, physical book sales turned up, from £2.74bn to £2.76bn.”
The idea behind a metal air battery is to use air—which is free, lightweight, and widely available—for the cathode part of the battery. Metal air batteries basically suck in the freely-available air and can ditch the heavy casing that would normally hold the anode material inside the battery. Using air basically makes these batteries fundamentally lighter and cheaper.
Fluidic Energy makes a specific type of metal air battery called a zinc-air battery. Zinc, which is abundant and low cost, is the key material that sits in the electrolyte of their battery and moves onto the anode during charging and discharging.
The 50-ton craft can carry as much as 20 tons of sensors or other gear and operates at depths reaching 11,000 feet. While on the surface, it downloads route instructions from human minders via satellite.
The Voyager runs on batteries, which are recharged using diesel fuel every three days during a four- to eight-hour resurfacing. With a full 1,000-gallon diesel tank, the robot can travel a total of 6,500 nautical miles—enough to swim around Australia—vs. 200 miles tops for a typical drone craft.
Electronic House’s winner this year is in a place we spent quite a bit of time in, as our son went to college there
“Conveniently from the app, which communicates directly with the home-based Crestron CP3-N processor, the owners can check out real-time weather conditions in Sarasota, and adjust the shades and HVAC system if necessary, which based on the brutal afternoon sun that hits this house, happens frequently. “The entire west side of the home that faces the water is made of 12-foot-tall glass walls,” says Bolduc. “So the home benefits greatly from having Lutron motorized shades to minimize solar gain and protect the furnishings from fading.”
Even if the owners aren’t on the app, the Crestron system handles the shade adjustments for them automatically. An astronomical timeclock built into the control processor triggers the shades to lower in unison in the afternoon. It’s an effect that not only shields the interior from heat and UV light, but makes the unoccupied home appear as if someone is at home.”
Roughly a billion cicadas will soon take over parts of Ohio, West Virginia, Virginia, Pennsylvania, Maryland and New York, filling the air with their raucous mating call.
The invasion only lasts six weeks. Once the baby cicadas, also called nymphs, have hatched from their eggs in the trees, they’ll fall to the ground and burrow into the soil, not emerging for another 17 years. Underground they survive off moisture from tree roots. Cicadas don’t eat solid food.
The adult cicadas are a gluten-free, low-fat, low-carb source of protein. They’re a favorite treat of dogs and cats.
The Rising Creek Bakery in Mount Morris, Pennsylvania, is making special cookies and custard to mark the 17-year occasion. Bakers freeze cicadas, remove their wings and coat them in sugar before placing them on top of a chocolate chip cookie or custard with caramel sauce, CBS Pittsburgh reported.
Today, it takes just seconds for Welder to learn that one of his company’s wells has gone down. That’s because in 2013, Welder Exploration became one of the first oil producers to sign on with WellAware, a tech startup that kits out clients’ oil and gas wells with hardware that transmits real-time data over its own radio network. Clients can access the information on a smartphone or tablet using WellAware’s mobile app or through a Web browser. Customers pay $15 to $100 a month per well, depending on the level of service and equipment.
Except for advances in drilling technology, which underpinned the U.S. shale boom, much of the oil industry remains strikingly antiquated when it comes to above-ground operations. Now, as companies transition from searching for deposits to slashing costs and improving the productivity of existing wells, digitizing their operations has become much more appealing.
Bigelow’s expandable station modules are made of as many as 30 layers of high-strength fabric, including Kevlar. They take up 127 cubic feet when compressed for launch.
Once in orbit, the modules fill with air from onboard tanks to expand to their intended size. The fabric resists impacts from micrometeoroids and debris more effectively than standard aluminum designs.
“If you still think Chinese tech companies are only about replicating the innovations that others have made, then you've got some catching up to do. Today's Chinese tech sector is filled with a number of disruptive companies that are not only competing but leaping ahead in the race to build better products and use tech to solve important problems.
I spent a week in Beijing in April, meeting with Chinese companies, talking with entrepreneurs and venture capitalists from across the globe, and getting a look inside some of the most important innovators on the Chinese mainland at GMIC Beijing 2016.”
He mentions Alibaba, Baidu, Didi, Hauwei, Tencent and several others. GMIC is the CES equivalent in China
Dell's new monitor will pique your interest, with a 43-inch 4K display and the option to run as four separate 1080p screens, without bezel breaks.The Dell P4317Q monitor can show content from four separate inputs simultaneously in full HD (four USB 3.0, two HDMI, one DisplayPort, one Mini DisplayPort, and one VGA port are available), and you can zoom in to any single display to take advantage of that 4K display at will. If you're considering throwing your multi-monitor setup out the window and going all-in with Dell — which the company says will save you 30 percent in energy consumption —prepare to spend some serious cash. This monitor will cost you $1,349 and is expected begin shipping on May 23rd.
Worn under Kanaan’s firesuit, the shirt acts as both fireproofing protection and sensor. The fabric of the shirt — not wires or a separate device — senses electrical activity.
“We’re not talking about a bracelet or a separate device; it’s the fabric itself,” said Adam Nelson, vice president, industry solutions, healthcare and life sciences at NTT Data, a Tokyo-based global system integration company. “Because it’s electroconductive polymer, it picks up the heart’s electrical activity. If you position the fabric on certain muscles, it picks up the muscle activity. … It’s a very different type of bio-signal that we capture with the fabric.”
Austin Burt, a professor of evolutionary genetics at Imperial College and the developer of the technology, didn’t set out to commit mosquito genocide. “Our target is malaria, not mosquitoes,” he says. “Mosquitoes are a means to an end.” But once unleashed, Burt’s mosquitoes have no kill switch. They will carry out their mission until there are no females left. To some experts, it’s a small sacrifice. But others worry about the implications of leaving a biological niche empty.
That concern is part of what drove Anthony James, a molecular biologist at the University of California, Irvine, to take a different tack. He’s working to make mosquitoes incapable of carrying malaria and, eventually, other pathogens like Zika. This technique leaves the mosquitoes in place while disarming them. “Nobody likes mosquitoes, but you can live with them if they are not giving you disease,” he says. “Better to fix the ones you have than deal with whoever comes along next.”
All the large food producers say they’re trying to reduce their financial dependence on sugar. In fleeing the storm, they’ve darted for varying types of cover. Coca-Cola has shrunk soda cans; Mondelēz International, the maker of Oreos, has become a power in the gluten-free movement; PepsiCo has tried shifting toward healthy-ish snacks such as hummus.
Nestlé has chosen a radically different path. It wants to invent and sell medicine. The products Nestlé wants to create would be based on ingredients derived from food and delivered as an appealing snack, not a pill, drawing on the company’s expertise in the dark arts of engineering food for looks, taste, and texture. Some would require a prescription, some would be over-the-counter, and some are already on store shelves today.
Google Home project lead Mario Querioz held the device in his palm, revealing a design that was shorter and wider than Amazon's cylindrical Echo, which is powered by Amazon's virtual assistant Alexa. Microsoft also has its own personal assistant, Cortana, but as yet no at-home device.
Google Home will use its new Google assistant, which leverages Google's search and the contextual queries it's been developing with a decade of research into artificial intelligence. It will be able to play music, complete a range of tasks and answer questions that one would ask of Google search.
Someday, the dusty back shelves of America's warehouses could be replaced by UPS and SAP-enabled 3-D printing.
To do that, the package-delivery company and business software company are working with an Atlanta-based company that has Louisville, Ky. production facilities called Fast Radius to do 3-D printing of parts.
Genetically engineered drugs known as biologics typically have to be injected rather than swallowed because their complex proteins break down in the stomach. Rani Therapeutics is developing a pill that will protect those proteins.
The patient swallows the pill, currently about the size of a large vitamin. The coating starts to dissolve when the pill reaches the high-alkaline level of the digestive tract, mixing its Alka-Seltzer-like components, which create carbon dioxide.
The CO2 inflates a small plastic-film balloon underneath one or two injector darts made of molded sugar, propelling them into the intestinal wall. The darts dissolve and the medicine they contain is absorbed into the bloodstream.
General Electric (GE) is known for creating technologies that can withstand thousands of degrees. To help the world better understand the stress those technologies are under, the company created a limited edition hot sauce called 1032K, named for the absolute hottest temperature (in Kelvin) at which matter can theoretically exist. The company only produced 1,000 bottles, all of which sold out shortly after it was announced – Popular Science
Harper’s Bazaar lists its top eateries with a great view to go along including 360 Bar & Dining “with sweeping views of the Sydney skyline, at the top of the Sydney Tower is a 'rooftop' you won't want to miss. With dark wood finishes and soft light sculptures, the mood sets itself as you dine on a 2-3 course meal of everything from oysters to handmade tagliatelle.”
Popular Science has several contraptions that could redefine breakfast for most including the Bacon Alarm Clock
Traditional alarm clocks wake you with annoying beeps. Tech entrepreneur Matty Sallin decided to make mornings more pleasant—with a bacon-scented alarm clock. “You probably have a memory of waking up to the smell of breakfast,” Sallin says. “It’s a completely effective alarm.” With help from friends, including engineer Josh Myer, he built a pig-shaped device. Partially inspired by the Easy-Bake oven, it uses two halogen lights to heat up precooked bacon in about 10 minutes. Once he’s awake, Sallin simply eats breakfast in bed.
the Parker Institute for Cancer Immunotherapy. PICI (pronounced “pie-sea”), as it’s called by its member scientists, is doing something unprecedented in academic medicine: combining and coordinating the efforts of six of the top cancer immunology centers in the country—MD Anderson Cancer Center, Memorial Sloan Kettering, Penn Medicine, Stanford, UCLA, and UCSF—in order to greatly expand and, more important, to accelerate our understanding of why some immune-based treatments work miraculously in some patients and not at all in others. Carl June, an oncologist at Penn and a PICI team member, says he almost can’t believe Parker pulled it off. “Never before would I think you could get all these institutions to sign the exact same document,” he says.
It’s only 20 minutes or so, and I think every young person should listen to Larry Ellison’s recent commencement speech at USC.
It is eloquent and inspirational about the ups and downs of life and discovering yourself:
“This was a pivotal moment in my life. My family was still mad at me for not going to medical school and now my wife was divorcing me because I lacked ambition. It looked like a reoccurrence of the same old problem. Once again I was unable to live up to the expectations of others. But this time I was not disappointed in myself for failing to be the person they thought I should be. Their dreams and my dreams were different. I would never confuse the two of them again.
I had discovered things that I loved; the Sierras, Yosemite, the Pacific Ocean. These natural wonders brought me great joy and happiness and would for the rest of my life. I had an interesting job programming computers and more money than I needed. For the first time I was certain that I was going to survive in this world. A huge burden of fear had been lifted. I'll never forget that moment. It was a time for rejoicing. I bought the sail boat and lived on board, just me and my cat, in Berkeley Marina. In the words of James Joyce, "I was alone and young and willful and unheeded, but I was happy and near to the wild heart of life.”
The old-school suitcase is getting an upgrade. Though innovation has been slow to hit the luggage industry, which accounts for $3.3 billion in revenue in the U.S., according to the Travel Goods Association, more companies have introduced high-tech luggage equipped with location tracking, phone chargers, and other savvy features that cater to connected travelers. Bluesmart and Samsonite were the first with smart bags, and now Tumi has partnered with AT&T T -1.01% and LugTrack to develop its Global Locator, coming later this year.